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Journal: Toxicology and applied pharmacology
Article Title: Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation.
doi: 10.1016/j.taap.2016.06.006
Figure Lengend Snippet: Fig. 7. Viability of U937 cells as estimated by cytofluorometric determination of DRAQ7 staining. Cells were treated as indicated for 24 or 48 h with the indicated drug. Results are expressed as the proportion of cells excluding the DNA stain. ANOVA indicated that the set of values is heterogeneous (24 h-treatments: P b 10−4; 48 h-treatments: P b 10−4). The effect of individual treatments was tested using Dunnett's test (**P b 0.01 vs. control values for each time point). Sample cell distributions (24 h-treatments) are shown as insets.
Article Snippet: Then, the
Techniques: Staining, Control